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MALIGNANCIES Annotation: Transcription factors (TFs) are important regulators of cell growth, development, and hematopoietic cell differentiation. Disrupting the mechanisms that are responsible for the proper
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references: 1) A. Sasukimar et al. Supramolecular covalency of halogen bonds revealed by NMR contact shifts in paramagnetic cocrystals. Chem. Sci. 2025, 16, 20239-20244. https://doi.org/10.1039/D5SC05769H . 2
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for understanding resistance mechanisms to BCR inhibitors, pre-clinical development of novel drugs and their combinations (several patents submitted by the lab). Recommended literature: Seda et al….Mraz FoxO1-GAB1
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. The project focuses on the development of molecular strategies for the delivery of anticancer drugs using macromolecular carriers. The successful candidates will work at the interface of organic and
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holds transformative potential for both basic biomedical research and pharmaceutical development, enabling direct analysis of drug-target engagement, binding affinities, and structural validation in
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modification profiles. This will provide new insights into the gene regulation mechanisms that control plant development and adaptation in response to environmental cues. Understanding how environmental cues