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: Investigate mechanisms of T-cell development, aging, and thymic involution using in vitro and in vivo models. Characterize and modulate the T-cell receptor (TCR) repertoire, including repertoire diversity
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ultimately reversed or rebuilt using bioengineering and synthetic biology approaches. The successful candidate will: Investigate mechanisms of T-cell development, aging, and thymic involution using in vitro
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kinetics of gene editors and RNA molecules to improve the precision and efficacy of gene therapies. Key Responsibilities Elucidate mechanisms of intracellular RNA trafficking using biomolecular assays and
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currently seeking a highly-motivated postdoctoral fellow to work on a research project focusing on mechanisms underlying cachexia in pancreatic and other gastrointestinal cancers. The centre is dedicated