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model/crop species with different levels of genome complexity. You will work very closely together with your dry-lab colleagues for data processing, training models, and the design of synthetic promoters
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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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critical roles of ion channels—particularly the TRP superfamily—in physiological and pathological processes. Our interdisciplinary approach spans from foundational electrophysiology to translational models
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are seeking a motivated and enthusiastic colleague with strong computational skills in the analyses of complex data sets to join our teams. About the project We have generated advanced brain on chip models
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researcher to study the complexity and heterogeneity of both mouse and human microglia in neurodevelopment and neurodegeneration. By using state of the art spectral flow cytometry you will develop advanced
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intervention trials (e.g., diet, FMT), and ex vivo gut models enabling advanced multi-omics analyses of these samples. In addition the lab also maintains a large culture collection, partially linked to genomic
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researcher to study the complexity and heterogeneity of both mouse and human microglia in neurodevelopment and neurodegeneration. By using state of the art spectral flow cytometry you will develop advanced
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the fundamental aspects of transcriptional control, this project also opens new avenues for the design of climate-resilient crops. Supported by single-cell profiling and predictive artificial intelligence models
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project that combines cutting-edge approaches including state-of-the-art imaging techniques, pluripotent stem cell models, in vivo mouse models of neurological disorders, drug (brain) delivery and nanobody
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in January 2025. The overarching goal is to identify the key factors controlling microbe-mediated carbon storage in the ocean, with a focus on using model microbial systems in the lab. We specialize in