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understand the function, regulation and biology of RNA:DNA hybrids termed R-loops. R-loops are three-stranded RNA-DNA hybrids of an RNA that invades an DNA duplex and are largely formed in a co-transcriptional
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PhD project: R-loops are secondary DNA structures consisting of an RNA-DNA hybrid and a single stranded DNA that can form behind the elongating RNA polymerase II during transcription. R-loops play
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the following PhD project: R-loops are three-stranded nucleic acid structures comprising an RNA hybrid and a displaced single-stranded DNA (ssDNA). The exposed ssDNA makes R-loops a hotspot for DNA modifications
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experience with algorithms relevant to computational biology documented programming skills, e.g. in Python and R very good communication and organizational skills with the ability to work to timelines, both
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the following PhD project: R-loops occur naturally during transcription and can have important regulatory functions, however, persistence of R-loops can have deleterious effects and result in the accumulation
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statistical data evaluation, creation of scientific programme codes using common software packages (MATLAB, Python, R) Simulation skills with e.g. molecular dynamics and alpha fold Knowledge
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modulate seedling development in a light-dependent manner. PhD project: Regulation of alternative splicing by R-loop formation in Arabidopsis R-loops refer to RNA-DNA hybrid structures that have been linked
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, both written and verbal Knowledge of German and/or a willingness to learn Computer/programming literacy, for example in R, and/or software used in image processing (Adobe Photoshop, ImageJ etc.) Ability
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experiences in working with remote sensing data, climate data and programming skills (R or Python) are desired. You enjoy working in an international team and you are keen on developing a key set of research
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Familiar with R, Python or other coding languages Experience with HPC clusters and Job Schedulers (e.g. SLURM) Interdisciplinary communication skills and intercultural competence Knowledge and experience in