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molecular and biochemical techniques to study metabolic enzyme function in the nucleus. Utilize genomics, proteomics, and metabolomics approaches to analyze chromatin regulation and transcriptional •responses
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- and triple recombinase systems, organoid culture, orthotopic transplantations of cells/organoids, CRISPR/Cas9, molecular in vivo imaging, quantitative proteomics/phosphoproteomics, multiple
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therapy response. Our lab has generated a comprehensive resource of cancer specimens and primary organoid cell cultures, which have been characterized at the genomic, transcriptomic and proteomic level to
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) in Computational Genomics (65 % E13 according to the TVöD salary scale). Responsibilities Integrative analysis of genomics datasets including but not limited to bulk and single-cell RNA-seq, proteomics
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facilities (on-site) in genomics, proteomics, imaging, and computational biology. Close supervision and mentorship to support scientific and career development. Financial support for conference participation
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editing, molecular biology, RNA analyses, fluorescence microscopy, recombinant protein expression/purification, in vitro biochemical assays Generating and analysing transcriptomic/metabolomics/proteomics
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the progression of aging processes. For both projects, the PhD student will utilise the expertise of the Sugimoto Lab, including high-throughput DNA sequencing, mass spectrometry-based proteomics, single-cell and
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instability, and dysregulation of R-loop processing is associated with cancer and neurodegenerative diseases. We have developed an unbiased mass spectrometry-based proteomics approach to identify proteins
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unrelated to their own. They attend practical courses in novel technologies (live imaging, genomics, proteomics, etc.) and soft skills courses (scientific writing, presentation skills, intellectual property
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plant development computational biology bioinformatics genomics and proteomics microbiology and microbiome science ecology evolutionary biology Our concept is supported by the facilities available