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Field
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The Schmid group at the University of Basel invites applications of talented and ambitious candidates for a PhD student position in the field of single-molecule biophysics, with a focus on protein
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in its capacity to resolve nanometer small conformational changes within single biomolecules (proteins, DNA, RNA), without suffering from ensemble averaging. Its Achilles heel is, however, photo
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the initiation and progression of neurodegenerative diseases including Parkinson's disease and Alzheimer's disease. In these disease contexts, microbiome-derived molecules, such as amyloidogenic proteins including
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discipline Solid wet-lab experience in molecular biology, ideally with tissue or protein work Motivation to develop bioinformatics and data analysis skills (training provided) Proficiency in English (spoken
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into cross-seeding between microbiome-borne amyloidogenic proteins and human proteins implicated in neurodegenerative disea Your responsibilities: The doctoral candidate will perform computational analysis
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cloning). Bacterial production of engineered proteins in E. coli or other microorganisms. Protein purification and characterization via IMAC, SEC, SDS-PAGE, WB, etc. Analysis of bacterial longevity and
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documentation and analysis of research data Development of experimental strategies to investigate and test scientific hypotheses Presentation of research findings and preparation of scientific publications
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Max Planck Institute for Multidisciplinary Sciences, Göttingen | Gottingen, Niedersachsen | Germany | 6 days ago
transmembrane cargo proteins and drive the formation of transport carriers within the endosomal network. In this mission, we primarily rely on cryo-ET and subtomogram averaging to visualize molecular machines in
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are a small international team based at the Max Planck Institute for Multidisciplinary Sciences in Göttingen, Germany. We aim to understand how molecular machines select transmembrane cargo proteins and
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) of membrane-bound proteins with high accuracy. Project Aims: Develop IMP-compatible cushioned supported bilayers. Establish protocols for IMP membrane insertion and interaction analysis using DMP. To develop