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this process. A specific cell population we are interested in are the endothelial cells of the blood brain barrier (BBB). It was shown before that these cells are capable of expressing MHCII and therefore could
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instability, and dysregulation of R-loop processing is associated with cancer and neurodegenerative diseases. We have developed an unbiased mass spectrometry-based proteomics approach to identify proteins
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of different DNA lesions. In addition to environmental (external) factors like UV, X-rays, ionizing radiations etc., cellular processes like hydrolysis, oxidation, alkylation, impediment to replication fork etc
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the following PhD project: Alternative splicing (AS) massively increases transcriptome complexity in higher eukaryotes, with critical implications in developmental processes and stress responses. Studying AS