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the following PhD project: Alternative splicing (AS) massively increases transcriptome complexity in higher eukaryotes, with critical implications in developmental processes and stress responses. Studying AS
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therefore teams up materialists, electrical engineers, and computer scientists of TUD, RWTH Aachen and Gesellschaft für Angewandte Mikro- und Optoelektronik mbH ( AMO ) in Aachen, Forschungszentrum Jülich
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instability. Our unpublished results indicate an unforeseen link between loss of specific tumor suppressors, increased R-loop formation and genome instability. Since unscheduled, persistent R-loops can trigger
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therefore teams up materialists, electrical engineers, and computer scientists of TUD, RWTH Aachen and Gesellschaft für Angewandte Mikro- und Optoelektronik mbH ( AMO ) in Aachen, Forschungszentrum Jülich
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therefore teams up materialists, electrical engineers, and computer scientists of TUD, RWTH Aachen and Gesellschaft für Angewandte Mikro- und Optoelektronik mbH ( AMO ) in Aachen, Forschungszentrum Jülich
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at the interface between biomedical engineering and mathematics. The following qualifications are required seeking your consideration for this position: • Excellent Master’s (or equivalent) degree in Numerical
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areas: software testing, runtime monitoring or diagnostics combined with a desire to embed these in today's assurance processes. Knowledge of software development methods (especially agile methods such as
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(scRNA-seq) and high-content protein profiling to compare wild type and mutant HSCs cells from iPSC and LT-HSCs cultures to delineate signaling pathways disturbed by leukemogenic mutations. We will then
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signals for their differentiation are required or if Th2 programs develop in the absence of classical activation cytokines. Our own research has identified a unique population of dermal dendritic cells
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(extravascular coagulation signaling) in homeostatic condition as well as in aging mouse models. Identification of these interactions could provide new approaches to counteract or delay age associated exhaustion