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the following PhD project: Alternative splicing (AS) massively increases transcriptome complexity in higher eukaryotes, with critical implications in developmental processes and stress responses. Studying AS
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therefore teams up materialists, electrical engineers, and computer scientists of TUD, RWTH Aachen and Gesellschaft für Angewandte Mikro- und Optoelektronik mbH ( AMO ) in Aachen, Forschungszentrum Jülich
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instability. Our unpublished results indicate an unforeseen link between loss of specific tumor suppressors, increased R-loop formation and genome instability. Since unscheduled, persistent R-loops can trigger
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at the interface between biomedical engineering and mathematics. The following qualifications are required seeking your consideration for this position: • Excellent Master’s (or equivalent) degree in Numerical
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areas: software testing, runtime monitoring or diagnostics combined with a desire to embed these in today's assurance processes. Knowledge of software development methods (especially agile methods such as
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(scRNA-seq) and high-content protein profiling to compare wild type and mutant HSCs cells from iPSC and LT-HSCs cultures to delineate signaling pathways disturbed by leukemogenic mutations. We will then
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signals for their differentiation are required or if Th2 programs develop in the absence of classical activation cytokines. Our own research has identified a unique population of dermal dendritic cells
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(extravascular coagulation signaling) in homeostatic condition as well as in aging mouse models. Identification of these interactions could provide new approaches to counteract or delay age associated exhaustion
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-year research assistant position (65% TV-L E13, ideal starting point in May/June 2025). In our group, we are interested in the role of protein import for establishment and maintenance of endosymbiotic
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. International networking and collaborations are regarded as an integral part of the PhD research experience and are explicitly encouraged (e.g. South America, Asia or Africa). The PhD process will be accompanied