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• Establishing an in vitro model for therapeutic screening • High throughput screening of several promising molecular therapeutics • Conducting an in vivo study to evaluate the molecular
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this project, using extensive primary cell culture, molecular analysis, scRNAseq, non-invasive imaging analysis, along with mechanistic studies using 2D/3D culture models, we will dissect the distinct cellular
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developing next-generation antimicrobial peptide (AMP)-based solutions targeting vaginal fungal infections, particularly Recurrent Vulvovaginal Candidiasis (RVVC). The project combines microbiology, molecular
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. Candidate profile: Applicants should hold or expect to receive an upper 2.1 or 1.1 degree in a relevant discipline. A cell biology/molecular biology/genomics background is essential. Training will be provided
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research is dedicated to improving the diagnosis and treatment of fungal infections. Additionally, we explore the biology of these infections, as well as the molecular mechanisms behind stress and antifungal
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, industry/EPA workshops, funded conference travel and short visits to partner labs Access to state-of-the-art modelling suites, class-1 monitoring equipment and the citizen-science platforms Position 1
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that these cells could be deployed to control intracellular S. aureus. The project will employ cutting edge technologies (transcriptomics, in vivo infection models, single cell metabolic analysis) to profile
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regression methods (e.g., fixed-effects growth curve models, staggered difference-in-differences) to analyse post-divorce economic trajectories. Synthetic control methods may be employed to establish causal
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the predictions of opaque models that are widely deployed in high-stakes decision making scenarios. Of particular interest to this project are example-based explanation methods that use individual data points
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, flexibility becomes an essential feature, driven by the development of flexible components and open networks. Development of Digital Twins, capable of building dynamic models from information gathered form live