Sort by
Refine Your Search
-
anti-cancer roles of these compounds via modulation of the immune system, with particular focus on effector (Teff) and regulatory (Treg) T cell populations. This project aims to identify changes in
-
Optimizing a 3D microfluidic IVD model to study cell responses to wear particles, refining culture conditions, and analysing cytotoxic and inflammatory mechanisms. Optimizing a 3D microfluidic IVD
-
PhD Scholarship in ‘Using nanoparticles to enhance the immune response and improve vaccine efficacy’
This project will examine the immune response to vaccines using various nanoparticle formulations and determine how they interact with cells to generate a strong immune response, capable
-
the age-related functional decline of immune cells has proven difficult. Many studies including ours have shown that epigenetic marks including DNA methylation and histone modifications play a fundamental
-
This scholarship aims to develop a spinal implant-on-a-chip platform to study the mechanobiological effects of wear particles on healthy IVD cells. The project involves generating clinically
-
or genetic tumor-specific risk factors, poor prognosis in ovarian cancer has been linked to a dysfunctional immune system. This includes presence of cells that turn off the immune system (e.g. regulatory T
-
’. We propose that the propensity of immune cells to respond by high cytokine production to environmental challenges is mechanistically associated with mood and particularly depression. Recent human
-
Cryopreservation of cells involves storage at very cold temperatures to minimise biochemical activity and prevent damage to the cells. However, the freezing process is damaging and requires
-
approaches to explore problems associated with membrane charge transport. Ion channels are proteins that control the movements of charged molecules across cell membranes to enable electrical activity in
-
of Vaccination over the Life Course.Annu Rev Cell Dev Biol. 2017 Oct 6;33:577-599. doi: 10.1146/annurev-cellbio-100616-060718. Previously, we and others have observed reduced vaccine efficacy in the elderly as