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calculation of mixture toxicity Development and application of chemical analytical methods Application of physiology-based kinetic (PBK) modelling for the extrapolation of in vitro to in vivo concentrations
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housing system on the welfare of laboratory animals and to compare it with the current standard housing conditions. Indicators of well-being include both the behaviour of the animals and physiological
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are an advantage: femtosecond laser and diagnostics, high power lasers, ultrahigh vacuum, programming skills (Labview, Python) Ability to work closely within a team: engineers, students, postdocs and scientists, and
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and entails 65 % of the full-time weekly hours. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz - WissZeitVG). The position offers
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Description About us: The Russo lab is a new research group in the Physiological Chemistry Department at the Biomedical Center (BMC) at the Ludwig-Maximilians-Universität (LMU) Munich, and is funded
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significantly hindered the development of suitable ocular therapies for the disease. To overcome this dilemma, we have decided to make use of advanced stem-cell technology and have established over the last years
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breadth PPIs, yet do not provide information on how proteins interact with each other. In fact, only for about 5% of all known human PPIs a structure of the interaction has been resolved. This lack in
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program between the Max Planck Institute of Molecular Physiology , the TU Dortmund University , the Ruhr University of Bochum , and the University of Duisburg-Essen , located in the vibrant and
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sarcomere characterize these structures as “cytoskeletal crystals” that form spontaneously inside muscle fiber cells. Yet, despite their physiological importance, we do not know how sarcomeres self-assemble
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processes, cell fate transitions during differentiation and cell maintenance. To understand their physiological role during human brain developmental processes and unravel disease-associated molecular