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developing body of evidence suggests caring is a risk factor for the development of cardiovascular disease. Suboptimal health status is described as a physical state between health and disease, characterised
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. The most frequent cause of deep ICH is deep perforating vasculopathy with hypertension being the most important risk factor. With the highest proportion of haemorrhagic strokes caused by undetected
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, trafficking, solubility, and their interactions with other proteins. Glycans vary in terms of glycosylic linkages, position of the hydroxyl group on the anomeric carbon, the number and type of constituent
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Apolipoprotein E (APOE) and the Brain Derived Neurotrophic Factor (BDNF), both individually and combined, account for some of this variation in cognitive decline the effects of other genes remain unclear
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) are potentially novel markers of Chronic Fatigue Syndrome, where N-glycosylation is the most common post-translational protein modification contributing to the heterogeneity of protein action, which is advantageous
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functional connectivity from a network perspective in healthy ageing (5) and also for neurodegenerative disorders (6) and neurological disorders post stroke (7-9). The mechanisms underlying emotion-cognition