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trials (e.g., diet, FMT), and ex vivo gut models enabling advanced multi-omics analyses of these samples. In addition the lab also maintains a large culture collection, partially linked to genomic data
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intervention trials (e.g., diet, FMT), and ex vivo gut models enabling advanced multi-omics analyses of these samples. In addition the lab also maintains a large culture collection, partially linked to genomic
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training data. You will unravel the cis-regulatory code controlling context-dependent gene expression and use this information to design synthetic promoters. You will train and evaluate predictive models in
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electrophysiology to translational models, including animal studies and analyses of human tissue samples. This full-stack methodology enables us to directly link molecular channel function with disease phenotypes
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critical roles of ion channels—particularly the TRP superfamily—in physiological and pathological processes. Our interdisciplinary approach spans from foundational electrophysiology to translational models
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diverse academic backgrounds to contribute to our projects in areas such as: Network Security, Information Assurance, Model-driven Security, Cloud Computing, Cryptography, Satellite Systems, Vehicular
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diverse academic backgrounds to contribute to our projects in areas such as: Network Security, Information Assurance, Model-driven Security, Cloud Computing, Cryptography, Satellite Systems, Vehicular
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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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the fundamental aspects of transcriptional control, this project also opens new avenues for the design of climate-resilient crops. Supported by single-cell profiling and predictive artificial intelligence models
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temperature signalling in plants, such as the model plant Arabidopsis thaliana and the crop plants wheat and soybean. To unravel this, we focus on dynamic changes in protein phosphorylation status, since