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Field
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pathogens as a model system. There are two post-doctoral research positions and one PhD studentship associated with Dr. McDonald’s UKRI Future Leader Fellowship, which will explore the cell biology
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research position is available for a highly motivated individual with strong expertise in modeling and simulation of biochemical reaction systems, with a focus on mRNA production from DNA templates
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responsible for building a simulator that allows researchers to see the response of their proposed mutations at DNA, RNA and protein levels. The candidate should have a deep understanding of the central dogma
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maintain viability within glaciers and permafrost. Duties will include conducting laboratory work such as DNA extraction, PCR, qPCR, making geochemical measurements; processing and analyzing molecular data
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of improved genetically encoded hypoxia reporters REQUIREMENTS: The candidate must hold a PhD in life sciences (obtained no longer than 3 years ago) A strong interest and experience in confocal and / or
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to investigate the underlying DNA damage response mechanisms in cancers. One area of active research is to investigate mechanisms of sensing and resolving R-loops in cancers to provide molecular insight
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research focuses on two areas: (1) how epigenetic memory—via Polycomb silencing and DNA methylation—is established and maintained, and (2) pattern formation in sub-cellular systems, particularly crossover
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hematopoietic cells, transplant assays Molecular biology approaches including western blot, RT-PCR, and DNA, RNA, and protein extraction, transfection. Immunology approaches including immunophenotyping, flow
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, genetic, and DNA methylation analyses to patient-derived samples and disease models. Working closely with a dynamic and multidisciplinary team of clinicians and scientists, they will help generate and
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take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches, including transcriptomic, genetic, and DNA methylation analyses to patient-derived