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performed an RNA-seq screen in mouse embryonic stem cells and neural progenitor cells and identified differentially expressed lncRNAs. The proposed studies will build upon these findings and use innovative
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and validating novel TPD molecules to target undruggable proteins. The Yeh Lab is a highly-collaborative environment with state-of-the-art facilities and expertise in biotherapeutics engineering and
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hematopoietic cell development and hematologic cancers. Based on these basic mechanistic insights, the Laboratory is building innovative therapeutics to treat hematopoietic cancers that are currently without
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of neural circuitry across rodent species to bridge this knowledge-gap. Position Requirements Candidates must hold a PhD degree (or equivalent) in neuroscience, biomedical engineering or a related field. The
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a relaxed and diverse atmosphere defined by constructive thought exchange. Opportunities to learn about model systems of disease, advanced microscopy, genetic engineering, new sequencing techniques
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outcome. The team uses a genetically engineered model of metastatic prostate cancer in a native, immune competent environment (see PMIDs: 24444712, 25829425 and 31092557). Recently, they developed whole