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familiar to you, and you're confident in leading conversations at a high level. Fluency in both Dutch and English, written and spoken, is essential for this role. What We Offer a leadership role with
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the most likely underlying neuropathological subtypes in FTD and AD patients. The project will make use of genetic information from the largest FTD and AD patient-control cohorts, including
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functional screens and read out mutation identities via barcode sequencing. By providing a direct link between sequence and function MAGESTIC enables massively scaled screens of precise mutations, with
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. The project investigates how food allergy affects gut-brain communication and function. Profile We are looking for a talented and curious individual with: A Master’s degree in immunology, neuroscience
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datasets for single nucleotide variants, structural variants, and tandem repeats relevant to FTLD Use cutting-edge bioinformatics software and methods, or develop novel tools when appropriate
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hypothesize that the coordinated proliferation of liver cells is orchestrated by evolutionary conserved molecular circuits that ensures liver function and avoids organ failure during the rapid neonatal tissue
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functional screens and read out mutation identities via barcode sequencing. By providing a direct link between sequence and function MAGESTIC enables massively scaled screens of precise mutations, with
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-cell module of hepatocytes, stellate cells, sinusoidal endothelial cells and Kupffer cells (Guilliams et al. Cell 2022 , Guilliams et al. Immunity 2022 ). Perturbing one part of the module leads to a
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murine microenvironments and use high-resolution spatial omics techniques to prioritize molecular factors that may drive the immune cell states. These will then be validated through in vivo screening
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, barrier tissue function, and the transition from homeostasis to disease. IRC combines molecular biotechnology, structural biology, cell biology, immunology, mouse genetics, bioinformatics, and translational