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the molecular mechanism of PPM1D degradation underlying its rapid turnover in normal conditions. We will also address how PPM1D associates with the chromatin which is another crucial determinant of its function
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compounds that modulate cilia-associated signaling in pathological conditions where ciliary function is impaired, such as ciliopathies or cancer. Candidate profile We are looking for an ethusiastic, curious
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: Doctoral researcher – Molecular and Developmental Biology Project title: Deciphering endocrine pancreas development and function at the single-cell level Understanding the different ways in which epigenetic
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-standing interest in the regulation of growth and metabolism. This interest stems from our early work on the pathway anchored by mTOR protein kinase, which we now appreciate is a major regulator of growth
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Technology in Prague, Czech Republic offers a Ph.D. position available from mid-2025. The position is related to the ongoing research of the group focused on the structure, function, and evolution
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Technology in Prague, Czech Republic offers a Ph.D. position available from mid-2025. The position is related to the ongoing research of the group focused on the structure, function, and evolution
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associated with miRNA pathway function and their defects in cancer and other pathologies. This position is funded by Project OP JAK – RNA for therapy, registration number: CZ.02.01.01/00/22_008/0004575
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multifaceted functions in homeostasis and diseases. They have traditionally been associated with type I allergies, such as rhinitis, asthma, and urticaria, causing a global health burden of approximately 20% of
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of independent research and development work within the CIDET project. • Cooperation with expert teams involved in the solution of the research direction devoted to the research and development of progressive
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: • Implementation of independent research and development work within the CIDET project. • Cooperation with expert teams involved in the solution of the research direction devoted to the research and development