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liver gene expression, with particular focus on cytosolic sulfotransferase family of drug- and endogenous molecule-metabolizing enzymes, in experimental models of human hepatocyte differentiation
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models and CRISPR technology, to address the important questions. This is an excellent opportunity to work on innovative and impactful research projects in a highly collaborative environment. We
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medicinal chemistry to available cellular and animal models of PDand is geared towards achieving groundbreaking steps in the field. Among the research approaches to be investigated are gene therapy, exosome
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and early-life development that span human cohort studies and animal models at Wayne State University in Detroit, MI. Projects comprise of multiple population-based studies including the Sperm
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behaviors from the dam. The proposed studies aim to use a translational rodent model to evaluate the effects of BUP compared to morphine on the maternal brain and behavior. Effects of gestational BUP and