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Malignancies: From Mechanisms to Therapies”. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate cancer cell plasticity in AML. Our
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Heidelberg University is a comprehensive university with a strong focus on research and international standards. With around 31,300 students and 8,400 employees, including numerous top researchers
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“Cellular Plasticity in Myeloid Malignancies: From Mechanisms to Therapies”. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate
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xenograft (PDX) models. To this end, the candidate will have direct access to cutting-edge mass spectrometry and advanced bioinformatics infrastructure. The project is part of the collaborative research
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“Cellular Plasticity in Myeloid Malignancies: From Mechanisms to Therapies”. In this CRC we will focus on myeloid malignancies as a model to dissect the various molecular mechanisms that enable and regulate
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of the synthetic peptide in chronic and acute heart failure animal models. The therapeutic peptide is derived from the protein S100A1, which plays a central role in maintaining normal heart function. The synthetic
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against cardiac diseases. It is based on extensive preliminary work by our working group, which has demonstrated therapeutic effects of the synthetic peptide in chronic and acute heart failure animal models
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adults, characterised by severe genomic instability and a lack of targeted therapies. Using cutting-edge methods and unique primary patient-derived cell models, this project will seek to understand
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department collaborates with numerous national and international partners and with local clinical and research departments. We offer a dynamic, interdisciplinary environment with extensive training
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of Heidelberg University Hospital, which is a leading center for research in Neuro-oncology and provides numerous training opportunities with access to cutting-edge techniques. The location in Heidelberg offers