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VLDL particles from heterozygous patients using ultracentrifugation. b. Assess VLDL-LDLR binding affinity via ELISA. c. Perform flow cytometry on HepG2 cells incubated with DiI-labeled VLDL
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systems (e.g. high-performance liquid chromatography (HPLC), particle size assessment (laser diffractometry (LD) and Dynamic Light Scattering (DLS)), release assays, differential scanning calorimetry (DSC
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