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/FRT-based dual and triple recombinase systems, orthotopic organoid transplantations, CRISPR/Cas9, quantitative proteomics / phosphoproteomics, multiple transcriptomics and genomics approaches, single
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long-read nanopore sequencing and deep mutational scanning of the screening output. This approach selects new, efficient enzymes, but also generates unique sequencefunction datasets that will be
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experimental protocols, including MR pulse sequence optimization and/or data acquisition strategies. Conduct MRI and/or high-density fNIRS measurements in healthy participants, following best practices in
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to the interior of the cell. GPCRs are involved in multiple physiological process including cell growth, neurotransmission, metabolism & immune response; they can misfunction in disease and consequently have served
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within a BSc/MSc thesis project. · Ability to effectively and reliably coordinate with the supervisor and multiple collaborators Language skills · Good level both written and spoken
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Deutsches Zentrum für Neurodegenerative Erkrankungen | Ulm, Baden W rttemberg | Germany | 23 days ago
sclerosis (ALS) and Parkinson’s disease. Using next-generation sequencing, we have identified Mendelian disease genes that cause autosomal-dominantly inherited ALS. We have developed innovative disease models
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data, quality assessment/filtering, alignment and variant detection. Experience with long-read (PacBio/ONT) NGS sequencing, genome assembly and annotation Strong competence in programming (shell/python/R
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results align with the abundance and expression of diatom ppRHO genes in the surface oceans. Research methodology Objective 1: Identify the subcellular localisation of two different ppRHOs isolated from
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University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations
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have a strong track record in bioinformatics to analyze bulk and single-cell RNA sequencing, proteomics, and lipidomics. Our Research Our team investigates the molecular pathways through which immune