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. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations. Be Bold
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) in an experimental model of multiple sclerosis (MS). This project builds on recent findings from the phase III Hercules trial (Fox et al., NEJM 2025) showing therapeutic effects of BTK inhibition in
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bioinformatics. The main responsibilities include: High-throughput sequencing: Applying long-read sequencing technologies (Oxford Nanopore) to quantify DVG populations in cells and virions without PCR bias (Direct
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employer in our industry. At UKE, we believe that meaningful and successful work should align with our employees' personal needs and individual lifestyles. Just as diverse as these needs are, so too is the
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of bacteria in the human gut, in-depth work with next-generation as well as 3rd generation sequencing technologies, then this PhD will be right for you. The ideal candidate will enjoy learning about metagenomic
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sequencing, metatranscriptomics and metagenomics to link taxa and functional genes (pmoA, mmoX, phnJ). Depth-resolved analyses will reveal which methanotroph taxa align more strongly with sediment fluxes
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aims to characterise the sequence, structural, and functional properties of UL-CDRs using deep learning and structural bioinformatics, with the goal of identifying novel antimicrobial peptide candidates
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treatment processes, and risk management? The Doctoral Researcher will receive interdisciplinary training across microbiology (culture-based and molecular, e.g., next-generation sequencing, bioinformatics
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subtype stx2a is linked to a higher chance of this progression and sequence-based surveillance has indicated increasing acquisition of this subtype across genetically diverse E. coli. In this project, we
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Each year, approximately 6,000 people in the UK are diagnosed with multiple myeloma. Despite advances in therapy, infections remain a leading cause of morbidity and early mortality in these patients