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validation, and regulatory reporter assays. Learn more about the group here . YOUR MISSION: Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing
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project description: Inkjet printing allows multiple materials to be 3D-printed simultaneously, useful for printing functional devices. Discovering the interactions of these materials and how to leverage
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project TARGET-AI will bring together expertise from multiple research groups to advance the state-of-the-art in combining the most advanced techniques from deep learning/AI with rigorous statistical
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- and long-read sequencing; computational and statistical analyses; a good mechanistic understanding of how cells replicate their DNA and respond to DNA damage. We Offer: Excellent framework conditions
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the era of large population size and dense genomic data such as whole-genome sequencing, new algorithms are needed to remove the bottleneck of computational load for such a development. In the frame of a
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and molecular tools (e.g., 16S rRNA gene sequencing, metagenomics, and metatranscriptomics). These interdisciplinary studies will further reveal if surfactants from glyphosate application can have
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“Quantitative predictions of protein – DNA interactions from high-throughput biophysical binding data”. Sequence specific binding and recognition between transcription factors and DNA control gene expression at
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Collaborative Doctoral Project (PhD Position) - AI-guided design of scaffold-free DNA nanostructures
-based digital twin, which can predict the assortment and sequence of two-dimensional all-DNA motifs required for the engineering desired tessellation patterns at the nanometer scale. We will use available
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Gene expression modulation CRISPR/Cas9 (including knock-out, knock-in, CRISPRa, CRISPRi, viral vector systems) Next-generation sequencing (RNA-, ATAC-, ChIP-Seq, CUT&RUN, Hi-C and others) Pulldown and
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University of Massachusetts Medical School | Worcester, Massachusetts | United States | about 1 month ago
their therapeutic potential both in vitro and in vivo that includes designing CRISPR-Cas targeting strategies, analyzes editing outcomes on a molecular level using next gen sequencing and ddPCR and conducts