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experienced research technologist and graduate student to harvest and process tissue samples. Perform single cell RNA sequencing of placental and fetal brain samples. Perform histological and imaging analyses
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samples. Perform single cell RNA sequencing of placental and fetal brain samples. Perform histological and imaging analyses of placental and fetal brain structure. Assess levels of hormones, growth factors
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writing. The successful candidate will have first-author publications in peer-reviewed journals and the ability to write research papers, with goal of multiple grant submissions in the first year. The
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cell culture Animal model of pulmonary hypertension Western blot and qPCR Immunohistochemistry. Single cell and ATAC sequencing. Statistical analysis. Supplemental Qualifications
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efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression
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is required. Further, knowledge in ATAC-sequencing, RNA-sequencing, pathological techniques, and in-vivo preclinical research experience is desirable.
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). Taking advantage of multiple state-of-the-art techniques (e.g., gene profiling, virus-mediated circuit tracing, calcium imaging/optrode recording, fiber photometry, EEG/EMG recordings, patch clamp slice
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, activated fibroblasts, and multiple mechanisms of immune suppression); identifying and disrupting molecular drivers of metastasis; and developing immune-based treatment strategies. Our ultimate aim is to take
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efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression