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leverage patient-derived material such as post-mortem tissue and cell models, including cellular reprogramming coupled with CRISPR gene editing. We use state-of-the-art sequencing methods e.g. Oxford
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of 3D genome and epigenomic landscape orchestrates gene expression programs that underlie neuron-to-glioma communication. In this project, we will use single-cell sequencing methods, bioinformatics, and
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this, we will apply novel tools based on semi-permeable capsules, including various analytical and biochemical methods, molecular barcoding, sequencing, and high dimensional data analytics. The project will
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(alpha-synucleinopathies) within the David Bäckström lab (umu.se), primarily multiple system atrophy (MSA) and dementia with Lewy bodies (DLB). Our aim is to understand what causes these diseases, how
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supervisors, aligning with your expertise and the needs of the program. Core tasks include study design, data acquisition, analysis, and interpretation of imaging data. Work responsibilities An appointment as a