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RAP opportunity at National Institute of Standards and Technology NIST Development of Technologies to Enable Single Molecule Protein Sequencing Location Material Measurement Laboratory
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RAP opportunity at National Institute of Standards and Technology NIST Design, Characterization, and Modeling of Sequence Controlled Polymers Location Material Measurement Laboratory, Materials
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distinct species or strains, and currently only molecular methods (e.g. polymerase chain reaction, sequencing) are able to differentially enumerate microbes in such a mixture. However, measurement bias in
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-generation” DNA sequencing, along with multiplexed affinity-based protein measurements. Technology development is based on microfluidic systems for cell manipulation and culture, and sample preparation
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include multiple laboratories featuring a range of collaborative and non-collaborative robots, industrial autonomous vehicles, mobile robots, mobile manipulators, state-of-the-art sensors, robotic hands
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that align DNA sequencing reads to the reference, but long and linked read sequencing technologies are now enabling haplotype-separated “de novo assembly” of human germline and cancer genomes. These methods
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identification of the constituents within complex microbial populations are a key area of need for biodefense, clinics, environmental, and microbiome analyses. Metagenomic sequencing holds the promise of enabling
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development, microfabricated device design and development, measurement of samples with ultrahigh throughput sequencing and microarrays, and bioinformatic/biostatistical data analysis of the large data sets
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simulation techniques. In addition, simulations and examination of the overall separation process may require computational studies across multiple length scales. key words Modeling; Nanotube; Molecular
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sensitive probe of crystalline order, conformational form, peptide sequence, solvent interactions, H-bonding force constants, and anharmonic character of the force fields. Continuous-wave and phase-coherent