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on genomic signatures, (2) use whole-genome-sequencing to discover population-level adaptation to different environmental constraints and (3) conduct enzymatic activity and gene expression experiments to test
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representatives of the Watkin’s collection for take-all suppression in the presence of different rhizosphere microbial communities conduct amplicon sequencing on the established communities to analyse how microbial
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datasets. Genome sequences are now available from half to a million people, meaning that we can expect to observe rare mutations at a large fraction of sites in the human genome. We can use this to try to
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their potential; many reported behaviours are strongly dependent on sample preparation and alignment and current fabrication routes restrict sample geometries thus limiting current applications. This PhD
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sequencing technologies - including metagenomics and transcriptomics - to explore the dynamic interplay between human gene expression and microbial communities. The successful candidate will develop and apply
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[s.eastham@imperial.ac.uk ]. Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities mentioned above. If you encounter
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the likely clinical outcome and aligning this with the patient’s known individual goals and preferences. The planned mixed-methods PhD will incorporate a scoping review, a data linkage study, and qualitative
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processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
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[Nature Biotechnology 2023, 41 1265], as well as novel approaches for the genome sequencing of modified bases and are exploring further base modifications, and how they interact with chromatin proteins (e.g
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research across three core areas of research competence: Circular Economy, Ecological Digital Citizenship, and Robotics & AI. These areas align with the EPSRC Discovery priority of Digital Futures, and the