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The Department of biochemstry and biophysics. The National Facility for In Situ Sequencing (ISS), located at SciLifeLab in Solna, provides state-of-the-art ISS technology to researchers across
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is aimed at a candidate with experience in wet lab and in bioinformatic analysis. We offer ample opportunities for professional development and specialization across various areas of work, in alignment
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that may remove such constraints, leading to a fundamental challenge: the potential co-existence of genetically distinct clones, each supporting multiple stable cancer cell states. To understand the effect
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and in vivo model systems, applying multiple omics methods. You will be working with clinical samples, method development and several molecular biology techniques, especially PCR and sequencing as
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). Particular emphasis is placed on HPC-supported computing of sequencing data into assembled transcripts (de novo assembly is a frequent need), and further downstream translation of the ORFs of said transcripts
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and occur in different assemblages that varies profoundly by both geography and time. Until now it has been difficult to study multiple pathogens simultaneously, but advances in sequence methodologies
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Solna in Stockholm. In the Marklund lab (marklundlab.com ), we investigate how sequence information in biological macromolecules governs recognition, binding, and dynamical structure. We combine high
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multiple locations in Sweden. It serves as the bioinformatics platform at SciLifeLab, a national resource that facilitates research in molecular biosciences by offering access to state-of-the-art
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central role in conducting laboratory-based experimental work using clinical samples, with a particular emphasis on microRNA profiling and whole-genome or exome sequencing, including metagenomic approaches
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“Quantitative predictions of protein – DNA interactions from high-throughput biophysical binding data”. Sequence specific binding and recognition between transcription factors and DNA control gene expression at