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Solna in Stockholm. In the Marklund lab (marklundlab.com ), we investigate how sequence information in biological macromolecules governs recognition, binding, and dynamical structure. We combine high
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multiple locations in Sweden. It serves as the bioinformatics platform at SciLifeLab, a national resource that facilitates research in molecular biosciences by offering access to state-of-the-art
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“Quantitative predictions of protein – DNA interactions from high-throughput biophysical binding data”. Sequence specific binding and recognition between transcription factors and DNA control gene expression at
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bioinformatics, with a particular emphasis on performing analysis of high-dimensional data, which can be sequencing and/or imaging-based. Experience working with AI and machine learning approaches are considered a
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). Particular emphasis is placed on HPC-supported computing of sequencing data into assembled transcripts (de novo assembly is a frequent need), and further downstream translation of the ORFs of said transcripts
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project: Computational methods for complex SV detection using sequencing data Main supervisor: Kristoffer Sahlin, ksahlin@math.su.se . Co-supervisor: Adam Ameur, adam.ameur@igp.uu.se . In the Department
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(or at all) by previous and ongoing genome sequencing efforts. The aim is to generate the first reasonably unbiased view of the insect tree of life, based on a backbone of some 5,000 genomes ‘decorated’ with
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evolutionary analysis. A central component of the research will be to develop machine learning and deep learning methods trained on coding sequences and protein structure to extract patterns in data and to draw
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-throughput sequencing of genomes and biomes, continuous recording of video and audio in the wild, high-throughput imaging of biological specimens, and large-scale remote monitoring of organisms or habitats
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from various tissue types, including specialized tissues (e.g., sperm), as well as quality control and library preparation for next-generation sequencing. Experience with advanced molecular and cellular