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esophageal organoids from both healthy and inflamed epithelium. You will characterize how inflammation impacts organoid development and architecture using IF and single-cell sequencing. In addition, you will
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the compositional genomic analyses in over a dozen sequencing consortia, whose results were published in Science, Nature, PNAS, and Genome Research. Dr. Elhaik's lab is famous for its population genomics and
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tetramers, BCR/TCR sequencing, single-cell multi-omics (RNA/ATAC/CITE/TCR-seq), and functional assays to map antiviral responses at high resolution. This project will be carried out as a close collaboration
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molecular tools (e.g., CRISPR-based genome engineering), computational algorithms, and DNA/RNA sequencing and synthesis to design useful cell behaviors. The scope of this project is to combine multi-gene
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The supervisor for this position, Dr. Eran Elhaik, led the compositional genomic analyses in over a dozen sequencing consortia, whose results were published in Science, Nature, PNAS, and Genome
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central role in conducting laboratory-based experimental work using clinical samples, with a particular emphasis on microRNA profiling and whole-genome or exome sequencing, including metagenomic approaches
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esophageal tissue using a variety of mouse models, organoid co-cultures and spatial sequencing technologies to identify relevant cell-cell interactions. We seek a curious, highly motivated, and creative
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profiling, cell culture, genome editing, single-cell sequencing, multi-omics analysis, and other relevant functional validation assays. Entry requirements Postdoctoral scholarships may be established
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responsibility of the successful candidate will be to conduct mainly functional assays, including handling human samples, immunological profiling, cell culture, genome editing, single-cell sequencing, multi-omics
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interdisciplinary, combining advanced molecular tools (e.g., CRISPR-based genome engineering), computational algorithms, and DNA/RNA sequencing and synthesis to design useful cell behaviors. The scope of this project