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validation, and regulatory reporter assays. Learn more about the group here . YOUR MISSION: Investigate how genetic variants affect male reproductive function Perform single-nucleus and bulk RNA sequencing
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Limitation:Temporary (3 years) Contract:TV-L Your tasks Infertility affects millions worldwide, yet in many cases the genetic basis remains unknown. Instead of focusing solely on gene-by-gene sequencing, this project
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Gene expression modulation CRISPR/Cas9 (including knock-out, knock-in, CRISPRa, CRISPRi, viral vector systems) Next-generation sequencing (RNA-, ATAC-, ChIP-Seq, CUT&RUN, Hi-C and others) Pulldown and
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and molecular tools (e.g., 16S rRNA gene sequencing, metagenomics, and metatranscriptomics). These interdisciplinary studies will further reveal if surfactants from glyphosate application can have
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-solving skills preferably skills in next generation sequencing-based methods and bioinformatics/computational data analysis Benefits: international working environment with communication in English and
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. The specific focus of the PhD projects will be tailored to the candidate’s interests and will align with the objectives of the aforementioned consortia. These projects work at the interface of the gut microbiome
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Collaborative Doctoral Project (PhD Position) - AI-guided design of scaffold-free DNA nanostructures
-based digital twin, which can predict the assortment and sequence of two-dimensional all-DNA motifs required for the engineering desired tessellation patterns at the nanometer scale. We will use available
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- and long-read sequencing; computational and statistical analyses; a good mechanistic understanding of how cells replicate their DNA and respond to DNA damage. We Offer: Excellent framework conditions
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analysis, next-generation sequencing, and small animal models. Salary and social benefits will be determined by the regulations of the German TV-AVH (salary agreement for public service employees
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step in eukaryotic gene expression, ensuring that mature transcripts are delivered from the nucleus to the cytoplasm for translation. Multiple challenges are faced in this process: How are mRNAs