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programme. Transposable elements (TEs) are defined as mobile genomic DNA sequences and are ubiquitous in all living organisms studied to date. These elements can constitute varying proportions
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sequencing, and mass spectrometry. With multidisciplinary research teams and a dynamic setting, the IBMC offers a stimulating environment conducive to scientific innovation. The IBMC is also affiliated with
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for epithelioid sarcoma, by characterizing epithelioid sarcoma models through state-of-the-art sequencing and molecular profiling techniques. The successful candidate is expected to develop experimental approaches
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, the PhD student will have at his/her disposition a set more than 150 high quality genomes (assembled from long-read sequencing and polished with short-reads), more than 100 of P. destructans and more
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activity (2, 3). This finding was unexpected because PCPE1 and PCPE2 are very similar in terms of sequences and structures. Objectives The main objectives of the PhD project will be (i) to elucidate
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the T4SS, test it through functional assays, and validate it using structural approaches. Main tasks Perform genetic constructions (cloning, mutagenesis, sequencing validation) and functional bacterial
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aims to provide an integrated assessment of urban vegetation from multiple perspectives, including its social functions and usage requirements, the ecosystem health of green spaces linked to plant
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for the identification of antibiotics-associated proteins and antimicrobial peptides Perform and support experimental studies across the METAMIC project, including notably metagenomic sequencing of field study samples
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. Good command of biostatistics (database management, use of R software) as well as an excellent level of English are essential. As eDNA data are amplified and sequenced independently, the involvement
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proteins (RIME) in a context where PRDM9 is present or absent, and the genomic localization of its known co-factor REC114 will be studied by ChIP followed by NGS sequencing. For a better mechanistic insight