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sample processing, high-throughput computing resources as well as next-generation sequencing and anaerobic microbiology facilities. You can build upon significant lab resources as well as guidance from a
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mortality rate. This project will involve a comprehensive approach combining bacterial whole genome sequencing, genomics based bio-informatics, chemical analyses of bacterial compounds and immunological
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) and has on-site robotic sample processing, high-throughput computing resources as well as next-generation sequencing and anaerobic microbiology facilities. You can build upon significant lab resources
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short and long-read sequencing and transcriptomics, and iPSC-based disease modeling to better understand the genetic etiologies of intractable epilepsy. The team is part of the European STXBP1 consortium
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for detecting multiple biomolecules, including nucleic acids, proteins, and other clinically relevant analytes. Position You prepare a doctoral thesis in the field of molecular quenching strategies
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scrambling. These splicing processes are regulated by cis-regulatory sequences and trans-acting splicing factors (SFs). While most mRNA isoforms produced from the same mucin gene locus encode similar
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of CRC-associated mucin mRNA isoform signatures in predicting the optimal therapy. These research objectives will be approached using established high-throughput next-generation sequencing, molecular
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microglia is a hallmark of neurodegenerative diseases such as multiple sclerosis (MS) and Alzheimer’s Disease (AD). These lipid-loaded microglia are associated with disease pathology and enhance
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this letter to introduce yourself and explain why you are a strong candidate, specifically addressing how your background and skills align with the research topic and the profile sought. Also confirm that you
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focus on non-coding ABCC6 variants and variants in novel disease genes, using whole genome sequencing (WGS). Next, validated biochemical assays will be used to evaluate the effect on protein function