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. We employ cutting-edge technologies including long-read sequencing, single-nuclei multi-omics, and iPSC-derived models to advance our understanding of disease biology and identify novel biomarkers
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-regulatory elements typically reduce translation of the primary coding sequence, whereas proteoforms are different protein isoforms translated from the same gene. This project aims to enhance both molecular
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functional screens and read out mutation identities via barcode sequencing. By providing a direct link between sequence and function MAGESTIC enables massively scaled screens of precise mutations, with
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-regulatory elements typically reduce translation of the primary coding sequence, whereas proteoforms are different protein isoforms translated from the same gene. This project aims to enhance both molecular
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innovative technologies. The VIB Technologies comprises multiple state-of-the-art core facilities, each with a specific technology focus and embedded within the VIB centers in Ghent, Leuven, or Brussels
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not limited to: DNA isolation, cloning and sequencing (including traditional Sanger sequencing and high throughput genomic sequencing), quantitative PCR, protein isolation and detection, RNAseq, and
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models. By utilizing biobanks of lung biopsies and established animal models, LifeLUNG will apply advanced machine learning and AI-driven deep sequencing to identify key immune factors and gene targets
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and cell-molecular techniques, including multi-parameter flow cytometry and single-cell RNA sequencing. The final objective of the research is to obtain a PhD. WHAT WE ARE LOOKING FOR You hold a
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, budgets, compliance, data, and impact monitoring; engaging with internal and external partners to shape translational project proposals; ensuring alignment with VIB’s Innovation & Business and Communication
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interactions using short-read and long-read sequencing technology You will help to characterize and quantify symbiont-mediated phenotypes in upcoming genetic model systems You will help to establish genetic