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pragmatic multi-centre trials of emerging and established imaging techniques within the NHS that ultimately change clinical practice. Our work is translational in nature, reflecting the interests and
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with the capability to centrally coordinate multi-centre clinical trials (i.e. having overall responsibility for the design, development, recruitment, data management and analysis of trials) with robust
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of the REFINE-MS trial, a multi-centre, phase 3 study led by Professor Olga Ciccarelli and Professor Max Parmar at UCL. The trial aims to identify the optimal dosing frequency of ocrelizumab in patients with
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