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to support a translational research project aiming to elucidate how microbiome dysbiosis, immunesenescence, and muscle ageing contribute to frailty. Through a combination of in vitro studies using models
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in vitro human models of the joint and musculoskeletal systems (chondrocytes, osteoblasts, myoblasts), vesicles released from adipose tissue will be characterised, their biodistribution tracked and
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