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, biomechanics, single cell-analyses, advanced imaging, and animal models. Tasks: to actively pursue the proposed project with the aim of characterizing the molecular, biomechanical and functional mechanisms
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Schizosaccharomyces pombe as a model organism. Representative publications include: Nature (2011), PMID: 21725325; Molecular Cell (2016), PMID: 27666591; Cell Reports (2016), PMID: 26832414; PNAS (2021), PMID
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Biochemistry, Molecular/Cell Biology, and/or BioEngineering documented by peer-reviewed publications Skills in a broad range of methods in the fields of Biochemistry, Molecular/Cell Biology, and/or
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heart disease as well as other medical conditions. We are determining single-cell based molecular mechanisms that are disrupted in mouse models of 22q11.2 deletion syndrome in early staged mouse embryos
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the Challenge Programme of the Novo Nordisk Foundation: “Mathematical Modelling for Microbial Community Induced Metabolic Diseases”, led by Prof. Daniel Merkle. The expected starting date is 1 Januar 2026, with
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explored. These strategies will be evaluated on cellular and mouse disease models, in order to determine whether APP editing can reduce pathogenic effects caused by amyloid-beta. In addition to gene editing
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mentoring at different levels. Previous experience in advanced tissue modeling and molecular and functional characterization is prerequisite, while experience working with bacterial cultures is a plus but not
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virological and immune system-based research through long-standing community partnerships and clinical trials research, along with using laboratory models of virus infection. The successful candidate will work
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from correcting disease-causing mutations, the potential of introducing protective mutations will be explored. These strategies will be evaluated on cellular and mouse disease models, in order to
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). The aim is to use modern molecular biological methods and in vivo models to investigate the role of fibroblastic plasticity in cardiac remodeling and loss of function. Your role: Independent work on the