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Republic, announces an opening for a PhD position in the area of molecular modeling of biomolecules with a focus on molecular dynamics simulations of nucleic acids and proteins. The candidate will be involved (among
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100%, Zurich, fixed-term We would like to announce a PhD position in molecular modeling of intrinsically disordered proteins constrained by EPR, cross-linking and NMR. Proteins in disperse and
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using optical activity, provide unique information about molecular structure and behavior. The interpretation of the spectra is often a challenging process, typically involving a combination of molecular
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, biophysics Machine learning and generative AI Molecular modeling and molecular dynamics simulations LNP formulation and characterisation including e.g. small angle scattering, microscopy, single particle
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, such as molecular data (e.g. omics), imaging, electronic health care records, longitudinal patient and population registries and biobanks. To be a doctoral student means to devote oneself to a research
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progression of pancreatic diseases. This project will entail a multi-disciplinary approach involving techniques of molecular biology, cell culture, and bioinformatics as well as animal modeling studies
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• Establishing an in vitro model for therapeutic screening • High throughput screening of several promising molecular therapeutics • Conducting an in vivo study to evaluate the molecular
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. The long-term goal is to enable targeted interventions for the right individuals, based on their lifestyle, disease trajectories, and molecular profiles. To achieve this, we will apply deep learning models
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microenvironment. Genetic deletion of GBPs in either GBM cells or TAMs reduces tumour growth and extends survival in preclinical models, highlighting their potential as dual-function therapeutic targets This project
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molecular mechanisms that drive its invasive behavior, both general and patient-specific. Using cutting-edge spatial techniques and CRISPR-based methods, we build data-driven models that link gene regulation