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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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since its discovery 150 years ago, due to a lack of model species 2,3. The candidate will use a combination of genetic tools to identify the molecular machinery responsible for chromosome fragmentation in
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understanding of the mechanisms that support their development in humans is therefore of major therapeutic interest. The aim of the thesis project is to decipher the cellular and molecular mechanisms supporting
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about the molecular basis underlying variation in these traits. Atlantic salmon is among the most variable vertebrates on Earth in terms of life histories, making it a powerful model to study how complex
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cells or the tumor microenvironment reduces tumor growth and extends survival in preclinical models, underscoring their potential as dual-function therapeutic targets. To address this, we aim to develop
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disciplines. Employees with different backgrounds conduct research in national and international research co-operations. The IGZ is based in Großbeeren near Potsdam and near Berlin and is a member of the
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scientific disciplines. Employees with different backgrounds conduct research in national and international research co-operations. The IGZ is based in Großbeeren near Potsdam and near Berlin and is a member
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, metabolomics, clinical samples, and animal models to accomplish these goals. The results will lead to the development of novel therapeutic strategies for the clinically relevant molecular subsets of lung cancer
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biological data, development of deep learning and large language models for biological discovery or graph-based methods for molecular and cellular networks. The technological foundation further consists