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Field
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those leading to dementia and neuroinflammation. We have a strong focus on mechanistic dissection of genetic, molecular cellular and neuropathological processes which underlie across the neurodegeneration
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discoveries (Mehra et al., Science, 2022), this project aims to identify novel genes and regulatory pathways involved in sensing water availability in the model plant Arabidopsis thaliana. We are particularly
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strategies, and preclinical efficacy studies. Key Responsibilities: · Design, rescue, and characterize recombinant VSV-based vectors using reverse genetics techniques. · Perform molecular cloning
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willing to work with the mouse as an animal model Conducting molecular neuroscience research using the mouse model in understanding the basis of long-term memory formation and the disorders associated with
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discoveries (Mehra et al., Science, 2022), this project aims to identify novel genes and regulatory pathways involved in sensing water availability in the model plant Arabidopsis thaliana. We are particularly
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-throughput measurements of molecular binding with simulations and quantitative modeling to gain a physical understanding of life at the molecular level. We are recruiting a Postdoctor that wants to use and
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. in Cancer Biology or a related field, with a strong foundation in molecular, cancer, and cell biology techniques and principles. A minimum of 2 years of experience working with animal models, such as
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seizure models and cell cultures, primarily utilizing molecular and cell biology techniques. The Obeid lab investigates the mechanisms of seizure emergence and their effects on cognitive and behavioral
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, immunohistochemistry, EEG/EMG in mice is strongly preferred. Experience in molecular cloning or computational modeling is a plus. The appointee should be organized, self-motivated and be able to work independently as
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healing. The Granville research program spans basic molecular biology and biochemistry through to target validation, proof-of-concept in animal and human models, and collaborations with clinicians and