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promise in understanding disease mechanisms and improving clinical decision-making. Recent studies suggest that generative models can uncover latent structures and improve classifier robustness across
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signalling, raising the possibility of shared molecular mechanisms. Project Aims This PhD project will focus on investigating the fibrotic behaviour of cells isolated from glaucoma patients of different ethnic
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identifying a novel biomarker for early decline in the heart-brain-axis, this study aims to explore the effect of alpha-synucleinopathy in heart and stellate ganglia. Using a PD animal model with a neuronal
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statistical models (for example principal component analysis) to obtain insights into relationships between physical properties of polysaccharides (composition, molecular weight charge, chain length etcetera
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About the Role Join a multi-disciplinary team that explores human intestinal development and disease using cutting edge single cell and spatial biology technologies, organoid models and
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materials modelling, with the goal of uncovering the fundamental structure–property relationships that govern material performance. You will be based 50% at the University of Birmingham in the Materials
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molecular biology, quantitative imaging and biophysical approaches to investigate cell shape changes in cultured cells and in vivo. Current projects in the lab include investigating the regulation
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modelling of laser shock peening. Molecular Dynamics (MD) and Finite Element (FE) simulations will be combined to account for the complex physical phenomena and their different scales. The interdependence
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spectroscopy and HPLC), organic synthesis, electrochemistry, hydrogel soft matter and modelling. You will be mentored by Dr. Maguire and will learn how to design and manage projects, how to conduct research, how
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and stem cell biology. The study investigates how APOE4 expression in endothelial cells affects oligodendrocyte progenitor cells (OPCs), using iPSC-derived 3D co-culture models. This work aims to