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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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microscopy) Flow cytometry Mammalian cell culture (cell models, including iPSC-derived cell lines) Lysosomal immunoprecipitation for multi-omics analysis Chemical synthesis Integration of biochemical, cellular
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research by: 🐟 Developing a smad3 knockout zebrafish model, 🔬 Optimizing in vivo visualization of aortic enlargement and molecular dysfunction, 💊 Developing a pathogenic signalling-based drug screening
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hearing impairment, yet the molecular basis of SNHL remains poorly defined. Using the Nipbl+/- mouse model, this project aims to: - Characterize inner ear development under Nipbl haploinsufficiency
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effective treatment for these diseases, and the project will entail a search for novel therapies in cell models, which could be moved onto animal models and eventually, affected patients. This will include
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into this type of research: actual nerve biopsies from patients with Charcot-Marie-Tooth neuropathy due to YARS1 mutations, along with matching iPSC-derived motor neurons and Drosophila models. Now, we
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. You will contribute by processing human samples, establishing mouse models, and performing molecular studies. You publish scientific papers related to the research project. You take on a limited set of
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. Our mission is to move beyond descriptive biology and develop predictive, mechanistic models that connect molecular regulation to cellular and systems-level phenotypes. The Laboratory of Computational
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. Our mission is to move beyond descriptive biology and develop predictive, mechanistic models that connect molecular regulation to cellular and systems-level phenotypes. The Laboratory of Computational
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Department: Center for Molecular Neurology Regime Full-time Let’s shape the future - University of Antwerp The University of Antwerp is a dynamic, forward-thinking, European university. We offer