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relevant to this project. Proven experience in molecular dynamics simulations of proteins or protein-ligand complexes is an advantage. You possess: A successfully completed MSc degree in computer science
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biochemical and molecular biology approaches, DNA and RNA sequencing and CRISPR-based genome editing to investigate the relationship between genome dynamics and topoisomerase activity. The PhD program at
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and single molecule assays to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello et al. Cell 2016; Wiegard et al. Molecular Cell 2021; Das et al
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in the soil, but also added by agricultural activities, especially the use of copper-based fungicides. In this project, we will combine multiple representative substance groups simulating
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resistome, i.e. all antibiotic resistance genes (ARGs) circulating in the gut, determine the microbiome dynamic, i.e. how an individual’s gut microbiome will respond to and recover from an antibiotic therapy