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of myotonic dystrophy type 1 and related disorders. 2. Perform laboratory experiments using appropriate molecular biology and genetic methodologies and interpret the results. 3. Perform statistical analysis
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We are seeking to appoint an experienced Laboratory Manager to work within the research area of molecular and cellular infection biology at the School of Infection and Immunity under the supervision
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Framework level 7 (Advanced Higher / HNC, SVQ 3), or equivalent in relevant science subject A2. Detailed technical knowledge of molecular biology, microbiology, and bacterial genetics. A3. Up to date
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research programme include molecular genetics (human, Drosophila and microbial genetics), biochemistry, molecular biology, systems biology, ‘omics (genomics, transcriptomics, proteomics, metabolomics
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and practical knowledge of plant molecular biology and plant photobiology A3. A comprehensive and up-to-date knowledge of the wider subject area or subject specialism A4. Specialist theoretical and
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gain expertise in molecular biological methods, and a deep grounding in the concepts of membrane transport, cell biology and physiology. Skills training will include in-depth engagement in molecular
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states. This PhD project aims to identify the molecular mechanism governing the functions of Staufen1 protein, using our unique expertise in the structural and quantitative biology of protein:nucleic acid
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. Techniques: CRISPR/Cas9 gene editing, molecular biology (including site directed mutagenesis), chromatin immunoprecipitation, immunoblotting, cell culture, real-time PCR References Somma D, Kok FO, Kerrigan D
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: microscopy, confocal microscopy, immunofluorescence, reporter genes References Beyenbach et al. "The developmental, molecular, and transport biology of Malpighian tubules." Annual review of entomology 55 (2010
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Facility (Dr R Burchmore, P Herzyk). This work is very much interdisciplinary, and adventurous, and requires not only a good foundation in basic molecular and cell biology, but also a willingness to learn