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state. The project will specifically investigate the role of endogenous retroelements in this context. Immune-functional consequences will be studied using in vivo mouse models, and in cell culture
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Opportunities to contribute to both basic and translational neuroscience Key Techniques: In vivo two-photon microscopy Genetically modified mouse models Molecular and cellular biology Small animal surgery
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state. The project will specifically investigate the role of endogenous retroelements in this context. Immune-functional consequences will be studied using in vivo mouse models, and in cell culture
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CRISPR/Cas9, cloning, protein biochemistry, as well as work with cell cultures and primary patient samples (S1/S2) Conducting and establishing experiments with in vivo mouse models Analysis and
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computational models to map co-expression networks and predict systemic disease transitions. Characterise intestinal microbiome changes and their correlation with inflammatory diseases. Computational modelling
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of inflammation remains the role of hypoxia. In this 3-year CRC (DFG)-funded position, we will use novel genetic reporters and transgenic models to specifically address the role of hypoxia during these processes
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us. Gender equality is an important aspect for us. To support work life balance we offer flexible working hours, variable part-time, job-sharing models and participation in mobile work (up to 50%). You
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-layer and cloud processes in the air-mass transformations that follow moist intrusion events into the Arctic. Using large-eddy simulation models, you will set up and run case studies of observed air-mass
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. In particular we use the promiscuous pregnane X receptor (PXR) and constitutive androstane receptor (CAR) as models. PXR and CAR transcriptionally regulate cytochrome P450 3A4 (CYP3A4) and CYP3A5-drug
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of how hotspots in human and marine mammal presence are distributed in affected areas. Acoustic ship models will furthermore help to understand and gauge the acoustic footprint of ships in various types