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experience in modeling system structures and behaviors. Initial experience with scientific publications or project work in the development of complex software systems, particularly in the software architecture
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experience with the complex phenotyping of immune cells and proficiency in working with in vivo animal models, including handling, experimental design and tissue sampling. If you are interested in this project
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for degradation? At the core of mRNA nuclear export works an evolutionary conserved machinery centered on a large protein complex: TREX. While we recently uncovered a mechanistic framework of the core of this
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, the details of the process are not yet fully understood. Mechanistic learning, the combination of mathematical mechanistic modelling and machine learning, enables a data-driven investigation of the processes
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affect their descendants. Due to the complexity of human epigenetics, we used C. elegans as a model to study the role of histone modifications on genome stability, longevity, and transgenerational
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explants, in vivo models and patient samples of type 2 immune disease will be critical to map and characterize key events that lead to different qualities of type 2 immunity and experimentally validate
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of Europe’s biggest research centers and help us to shape change! Are you eager to pursue a four-year doctoral project that bridges scientific disciplines? Are you excited by complex societal challenges
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phenomena such as the spread of misinformation or the formation of filter bubbles. For this, we rely on rigorous probabilistic methods to model and analyse the intrinsic complexities of these systems
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and their interactions with the immune system, while also investigating new compounds with potential therapeutic effects. The department VIRI studies viral infections in animal models and in models
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, biophysical and bio-chemistry, theoretical chemistry and mathematics , to advance the understanding of the emergence of complexity in molecular systems. Our RTG combines science and research projects that start