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Immunoprecipitation Mass spectrometry of Endogenous complexes). We have identified about 50 proteins that can associate with Ascl1 or other NEPC transcription factors, some of which are enzymes that could in theory be
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microscopies, ultrafast photophysics, X-ray, THz, superresolution, modelling. Further details including funding information is available at: www.nanodtc.cam.ac.uk/apply/ For entry in October 2026, applications
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using