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model/crop species with different levels of genome complexity. You will work very closely together with your dry-lab colleagues for data processing, training models, and the design of synthetic promoters
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-scale screens to study fundamental principles in molecular and complex trait genetics using microbes as model systems. Our core technology MAGESTIC (https://doi.org/10.1038/nbt.4137 ), a CRISPR/Cas9-based
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critical roles of ion channels—particularly the TRP superfamily—in physiological and pathological processes. Our interdisciplinary approach spans from foundational electrophysiology to translational models
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are seeking a motivated and enthusiastic colleague with strong computational skills in the analyses of complex data sets to join our teams. About the project We have generated advanced brain on chip models
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researcher to study the complexity and heterogeneity of both mouse and human microglia in neurodevelopment and neurodegeneration. By using state of the art spectral flow cytometry you will develop advanced
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intervention trials (e.g., diet, FMT), and ex vivo gut models enabling advanced multi-omics analyses of these samples. In addition the lab also maintains a large culture collection, partially linked to genomic
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the fundamental aspects of transcriptional control, this project also opens new avenues for the design of climate-resilient crops. Supported by single-cell profiling and predictive artificial intelligence models
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project that combines cutting-edge approaches including state-of-the-art imaging techniques, pluripotent stem cell models, in vivo mouse models of neurological disorders, drug (brain) delivery and nanobody
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in January 2025. The overarching goal is to identify the key factors controlling microbe-mediated carbon storage in the ocean, with a focus on using model microbial systems in the lab. We specialize in
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temperature signalling in plants, such as the model plant Arabidopsis thaliana and the crop plants wheat and soybean. To unravel this, we focus on dynamic changes in protein phosphorylation status, since