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biopsies and in a newly developed swine ALS model. The postholder will lead wet-lab experimental work, across biophysical (MANT-ATP) and functional genomic assays (methylome, transcriptome and proteome
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individual muscle fibre, this project will determine the subtype-specific dysregulation of SkM in ALS, both in human patient biopsies and in a newly developed swine ALS model. The postholder will lead wet-lab
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pipeline for cochlear tissue that is suitable to translate to our various mouse models we currently have running in the lab. There will also be good opportunity to collaborate with other members of the Nolan
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administering standardised or experimental assessments. Competence in data analysis and databased management, including techniques relevant to longitudinal studies (e.g. mixed models, SEM, in R, Stata, MPlus
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various mouse models we currently have running in the lab. There will also be good opportunity to collaborate with other members of the Nolan lab working on aligned projects. The post would suit somebody
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assessments. Competence in data analysis and databased management, including techniques relevant to longitudinal studies (e.g. mixed models, SEM, in R, Stata, MPlus, or other suitable programme) Proven ability